Genes that increase preterm birth risk identified

preterm birthU. S. government researchers on Thursday said that a great cause for death in infant and disability is mother’s genes. Genes play a role in the threat of preterm labor.

Researchers informed that inflammatory response to infections inside the uterus take places due to genes. This raises the risk of a baby being born premature.

Dr Roberto Romero of the National Institutes of Health, said, "Preterm birth costs the United States $26 billion per year. It is one of the most serious and significant challenges to medicine and society and one whose importance is not fully recognized." He presented his findings at a meeting of the Society for Material-Fetal Medicine in Chicago.

About 190 genes and more than 700 DNA variants that were collected from 229 women and 179 premature infants in Chile were analyzed for studies by a team. The collected lot was compared to genes from 600 women who delivered their babies full term.

Romero after conducting the study said, "What we found was there were some DNA variants in the fetus that were associated with the occurrence of premature labor and delivery, and there were some genes in the mother that also increase the risk of premature labor and delivery."

The strongest influence in the fetus was the interleukin 6 receptor gene. This gene is also responsible for the body's response to inflammation.