Drug Devised to Reduce Obesity

Drug Devised to Reduce ObesityJournal Science Translational Medicine published research has revealed that the US researchers have devised a drug, Adipotide, which has proved success among obese monkeys and mice.

Co-Lead researcher, Professor Renata Pasqualini was of the view that before experimenting drug on rhesus monkeys, they conducted experiment on obese mice. It was found that mice were able to lose 30% of their body weight.

It was only after the success of pre-clinical testing that they decided to have clinical test on rhesus monkeys. After the drug was given to them, it was found that they were able to reduce 11% of their body weight, and also reduced their increased waist line and their BMI also declined.

Adipotitde works to reduce white adipose tissues, a white colored fat that accumulates under the skin and around the stomach. It is the one which increases the risk of cancer and other problems like diabetes and blood pressure.

It is quite different from other weight lose treatment as neither it restricts to have limited diet nor it tries to artificially enhance metabolism level. This drug tries to treat obesity by reducing white deposited fat.

Pasqualini affirmed, "Development of this compound for human use would provide a non-surgical way to actually reduce accumulated white fat, in contrast to current weight-loss drugs that attempt to control appetite or prevent absorption of dietary fat".

Success of primate experiment has made them to use it on humans as well, and the good news is that there is no side effect of this drug.

Toe groups were taken one group was treated with the drug, while other set of obese monkeys were not treated. After four weeks, it was found that drug treated monkeys have lost weight.

Researchers were of their view that soon they would be starting their human clinical trials as it not only reduces obesity but prostate cancer as well.