Cancer survival up by 30 pct by Sanofi drug

Sanofi-AventisA new research stated that a 30 per cent boost in the survival rate of men with prostate cancer whose tumors no longer respond to standard treatment was seen with Sanofi-Aventis's (SASY. PA) experimental chemotherapy drug Jevtana.

Prospects of the drug are bright and the drug might be able to offset the French drugmaker's loss of patent protection on its existing blockbuster cancer medicine Taxotere later this year following these results based on an international Phase III clinical trial.

Sanofi had already announced that goals were met by Jevtana, or cabazitaxel, in the 755-patient trial.

Study leader Oliver Sartor of Tulane Cancer Center in New Orleans said, “The unequivocal survival benefit gave hope to men with metastatic castration-resistant prostate cancer whose disease continues to grow despite standard chemotherapy. This agent will provide an important new therapeutic option for men with this advanced form of prostate cancer.”

Patients who were administered Jevtana and the older drug prednisone during the trial lived a median of 15.1 months as compared to patients who lived 12.7 months after taking mitoxantrone and prednisone.

There were certain experiences like fever with declines in white blood cell counts in 7.5 per cent of men who were on Jevtana as compared to only 1.3 per cent of those who took mitoxantrone.