Doctors get varied responses to quit-smoking treatments

Smoking2Scientists have an increasing portfolio of evidence that tobacco smoke affects the DNA of different people in different ways. They said that individual smokers inhale differently and conversely and also the tools that they used to break free from this addiction does not work in the same way in everyone.

Addiction to nicotine, therefore, is not a one-size-fits-all problem. One of the studies reported in July this year that humans have at least 323 genes whose expression levels are affected by smoking behaviors.

Southwest Foundation for Biomedical Research in San Antonio had researchers conduct a study on white blood cells taken from 1,240 people, Including 297 present smokers to identify changes in gene expression from exposure to cigarette smoke.

Jac Charlesworth, lead author of the study published in the British journal BMC Medical Genomics said, “The scale at which exposure to cigarette smoke appears to influence the expression levels of our genes is sobering.”

The team led by her discovered important changes in the expression of smokers of genes which influence the immune system, cell death, cancer and metabolism of foreign particles compared to what was observed among non-smokers.